研究業績

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2015年研究業績

英文総説

  1. Teshima T. The primacy of IL-6 in IPS?. Blood. 2015 Apr 9;125(15):2320-2.
  2. Ogata M, Fukuda T, Teshima T. Human herpesvirus-6 encephalitis after allogeneic hematopoietic cell transplantation: what we do and do not know.Bone Marrow Transplant. 2015 Aug;50(8):1030-6.

英文原著

  1. Uryu H, Hashimoto D, Kato K, Hayase E, Matsuoka S, Ogasawara R, Takahashi S, Maeda Y, Iwasaki H, Miyamoto T, Saijo S, Iwakura Y, Hill GR, Akashi K, Teshima T.:α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice.:Blood. 2015 May:7;125(19):3014-23.
  2. Sugita J, Kawashima N, Fujisaki T, Kakihana K, Ota S, Matsuo K, Miyamoto T, Akashi K, Taniguchi S, Harada M, Teshima T; Japan Study Group for Cell Therapy and Transplantation..HLA-Haploidentical Peripheral Blood Stem Cell Transplantation with Post-Transplant Cyclophosphamide after Busulfan-Containing Reduced-Intensity Conditioning.:Biol Blood Marrow Transplant. 2015 Sep;21(9):1646-52.
  3. Shiratori S, Ohigashi H, Ito S, Kudo K, Adachi M, Minamimoto T, Kato J, Osai Y, Tsutsumi Y, Teshima T.:Late onset toxic epidermal necrolysis induced by mogamulizumab, an anti-CC chemokine receptor 4 antibody for the treatment of adult T-cell leukaemia/lymphoma:Hematol Oncol. 2015 Jul 14.
  4. Shiratori S, Fujimoto K, Nishimura M, Hatanaka KC, Kosugi-Kanaya M, Okada K, Sugita J, Shigematsu A, Hashimoto D, Endo T, Kondo T, Abe R, Hashino S, Matsuno Y, Shimizu H, Teshima T.:Allogeneic hematopoietic stem cell transplantation following reduced-intensity conditioning for mycosis fungoides and Sezary syndrome.:Hematol Oncol. 2016 Mar;34(1):9-16.
  5. Shiratori S, Kosugi-Kanaya M, Shigematsu A, Kobayashi H, Yamamoto S, Kobayashi N, Iwasaki H, Mori A, Kunieda Y, Yutaka T, Kurosawa M, Kakinoki Y, Endo T, Kondo T, Hashino S, Teshima T; North Japan Hematology Study Group (NJHSG)..:Ultra-high level of serum soluble interleukin-2 receptor at diagnosis predicts poor outcome for angioimmunoblastic T-cell lymphoma.:Leuk Lymphoma. 2015;56(9):2592-7.
  6. Nishida M, Shigematsu A, Sato M, Kudo Y, Omotehara S, Horie T, Iwai T, Endo T, Iguchi A, Shibuya H, Hatanaka K, Shimizu C, Teshima T.:Ultrasonographic evaluation of gastrointestinal graft-versus-host disease after hematopoietic stem cell transplantation.:Clin Transplant. 2015 Aug;29(8):697-704.
  7. Hayase E, Kurosawa M, Suzuki H, Kasahara K, Yamakawa T, Yonezumi M, Suzuki S, Teshima T.:Primary Bone Lymphoma: A Clinical Analysis of 17 Patients in a Single Institution.:Acta Haematol. 2015;134(2):80-5.
  8. Takemura R, Takaki H, Okada S, Shime H, Akazawa T, Oshiumi H, Matsumoto M, Teshima T, Seya T.:PolyI:C-Induced, TLR3/RIP3-Dependent Necroptosis Backs Up Immune Effector-Mediated Tumor Elimination In Vivo.:Cancer Immunol Res. 2015 Aug;3(8):902-14.
  9. Takahashi S, Kasamatsu J, Azuma M, Matsumoto M, Morii-Sakai A, Imamura M, Teshima T, Takahashi A, Hirohashi Y, Torigoe T, Sato N, Seya T.:PolyI:C and mouse survivin artificially embedding human 2B peptide induce a CD4+ T cell response to autologous survivin in HLA-A*2402 transgenic mice.:Immunobiology. 2015 Jan;220(1):74-82.
  10. Onozawa M, Goldberg L, Aplan PD.:Landscape of insertion polymorphisms in the human genome.:Genome Biol Evol. 2015 Mar 4;7(4):960-8.
  11. Shibayama Y, Kondo T, Ohya H, Fujisawa S, Teshima T, Iseki K.:Upregulation of microRNA-126-5p is associated with drug resistance to cytarabine and poor prognosis in AML patients.:Oncol Rep. 2015 May;33(5):2176-82.
  12. Tsutsumi Y, Shimono J, Ohhigashi H, Ito S, Shiratori S, Teshima T.:Analysis of the influence of dabigatran on coagulation factors and inhibitors.:Int J Lab Hematol. 2015 Apr;37(2):225-30.
  13. Takahata M, Hashino S, Nishio M, Sugita J, Shigematsu A, Onozawa M, Fujimoto K, Endo T, Kondo T, Tanaka J, Imamura M, Teshima T.:Occurrence of adverse events caused by valganciclovir as pre-emptive therapy for cytomegalovirus infection after allogeneic stem cell transplantation is reduced by low-dose administration.:Transpl Infect Dis. 2015 Dec;17(6):810-5
  14. CSuehiro Y, Hasegawa A, Iino T, Sasada A, Watanabe N, Matsuoka M, Takamori A, Tanosaki R, Utsunomiya A, Choi I, Fukuda T, Miura O, Takaishi S, Teshima T, Akashi K, Kannagi M, Uike N, Okamura J.:linical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study.:Br J Haematol. 2015 May;169(3):356-67.
  15. Eriguchi Y, Nakamura K, Hashimoto D, Shimoda S, Shimono N, Akashi K, Ayabe T, Teshima T.:Decreased secretion of Paneth cell α-defensins in graft-versus-host disease.:Transpl Infect Dis. 2015 Oct;17(5):702-6.
  16. Shima T, Iwasaki H, Yamauchi T, Kadowaki M, Kiyosuke M, Mochimaru T, Takenaka K, Miyamoto T, Akashi K, Teshima T.:Preserved in vivo reconstitution ability of PBSCs cryopreserved for a decade at -80 °C.:Bone Marrow Transplant. 2015 Sep;50(9):1195-200.
  17. Yutaka T, Ito S, Ohigashi H, Naohiro M, Shimono J, Souichi S, Teshima T.:Sustained CD4 and CD8 lymphopenia after rituximab maintenance therapy following bendamustine and rituximab combination therapy for lymphoma.:Leuk Lymphoma. 2015;56(11):3216-8.
  18. Nakasone H, Fukuda T, Kanda J, Mori T, Yano S, Kobayashi T, Miyamura K, Eto T, Kanamori H, Iwato K, Uchida N, Mori S, Nagamura-Inoue T, Ichinohe T, Atsuta Y, Teshima T, Murata M; GVHD working group of the Japan Society of Hematopoietic Cell Transplantation..:Impact of conditioning intensity and TBI on acute GVHD after hematopoietic cell transplantation.:Bone Marrow Transplant. 2015 Apr;50(4):559-65.
  19. Takashima S, Miyamoto T, Kamimura T, Yoshimoto G, Yoshida S, Henzan H, Takase K, Kato K, Ito Y, Ohno Y, Nagafuji K, Eto T, Techima T, Akashi K.:Effects of conditioning intensity in allogeneic stem cell transplantation for Philadelphia chromosome‑positive acute lymphoblastic leukemia.:Int J Hematol. 2015 Dec;102(6):689-96.
  20. Arai S, Arora M, Wang T, Spellman SR, He W, Couriel DR, Urbano-Ispizua A, Cutler CS, Bacigalupo AA, Battiwalla M, Flowers ME, Juckett MB, Lee SJ, Loren AW, Klumpp TR, Prockup SE, Ringdén OT, Savani BN, Socié G, Schultz KR, Spitzer T, Teshima T, Bredeson CN, Jacobsohn DA, Hayashi RJ, Drobyski WR, Frangoul HA, Akpek G, Ho VT, Lewis VA, Gale RP, Koreth J, Chao NJ, Aljurf MD, Cooper BW, Laughlin MJ, Hsu JW, Hematti P, Verdonck LF, Solh MM, Norkin M, Reddy V, Martino R, Gadalla S, Goldberg JD, McCarthy PL, Pérez-Simón JA, Khera N, Lewis ID, Atsuta Y, Olsson RF, Saber W, Waller EK, Blaise D, Pidala JA, Martin PJ, Satwani P, Bornhäuser M, Inamoto Y, Weisdorf DJ, Horowitz MM, Pavletic SZ; Graft-vs-Host Disease Working Committee of the CIBMTR..:Increasing incidence of chronic graft-versus-host disease in allogeneic transplantation: a report from the Center for International Blood and Marrow Transplant Research.:Biol Blood Marrow Transplant. 2015 Feb;21(2):266-74
  21. Schmeel LC, Schmeel FC, Kim Y, Blaum-Feder S, Endo T, Schmidt-Wolf IG.:In vitro efficacy of cinnarizine against lymphoma and multiple myeloma.:Anticancer Res. 2015 Feb;35(2):835-41.
  22. Tan EJ, Kahata K, Idås O, Thuault S, Heldin CH, Moustakas A.:The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition.Nucleic Acids Res. 2015 Jan;43(1):162-78.
  23. Suenaga F, Ueha S, Abe J, Kosugi-Kanaya M, Wang Y, Yokoyama A, Shono Y, Shand FH, Morishita Y, Kunisawa J, Sato S, Kiyono H, Matsushima K.:Loss of lymph node fibroblastic reticular cells and high endothelial cells is associated with humoral immunodeficiency in mouse graft-versus-host disease.:J Immunol. 2015 Jan 1;194(1):398-406.
  24. Aoki T, Suzuki R, Kuwatsuka Y, Kako S, Fujimoto K, Taguchi J, Kondo T, Ohata K, Ito T, Kamoda Y, Fukuda T, Ichinohe T, Takeuchi K, Izutsu K, Suzumiya J.:Long-term survival following autologous and allogeneic stem cell transplantation for blastic plasmacytoid dendritic cell neoplasm.:Blood. 2015 Jun 4;125(23):3559-62.
  25. Moskalenko M, Pan M, Fu Y, de Moll EH, Hashimoto D, Mortha A, Leboeuf M, Jayaraman P, Bernardo S, Sikora AG, Wolchok J, Bhardwaj N, Merad M, Saenger Y.:Requirement for innate immunity and CD90⁺ NK1.1⁻ lymphocytes to treat established melanoma with chemo-immunotherapy.:Cancer Immunol Res. 2015 Mar;3(3):296-304.
  26. Aoki J, Kanamori H, Tanaka M, Yamasaki S, Fukuda T, Ogawa H, Iwato K, Ohashi K, Okumura H, Onizuka M, Maesako Y, Teshima T, Kobayashi N, Morishima Y, Hirokawa M, Atsuta Y, Yano S, Takami A.:Impact of age on outcomes of allogeneic hematopoietic stem cell transplantation with reduced intensity conditioning in elderly patients with acute myeloid leukemia.:Am J Hematol. 2016 Mar;91(3):302-7.
  27. Schmeel LC, Schmeel FC, Kim Y, Blaum-Feder S, Endo T, Schmidt-Wolf IG.:Flunarizine exhibits in vitro efficacy against lymphoma and multiple myeloma cells.:Anticancer Res. 2015 Mar;35(3):1369-76.
  28. Cui Y, Onozawa M, Garber HR, Samsel L, Wang Z, McCoy JP, Burkett S, Wu X, Aplan PD, Mackall CL.:Thymic expression of a T-cell receptor targeting a tumor-associated antigen coexpressed in the thymus induces T-ALL.:Blood. 2015 May 7;125(19):2958-67.
  29. Shichino S, Abe J, Ueha S, Otsuji M, Tsukui T, Kosugi-Kanaya M, Shand FH, Hashimoto S, Suzuki HI, Morikawa T, Inagaki Y, Matsushima K.:Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice.:Am J Pathol. 2015 Nov;185(11):2923-38.
  30. Inamoto Y, Flowers ME, Wang T, Urbano-Ispizua A, Hemmer MT, Cutler CS, Couriel DR, Alousi AM, Antin JH, Gale RP, Gupta V, Hamilton BK, Kharfan-Dabaja MA, Marks DI, Ringdén OT, Socié G, Solh MM, Akpek G, Cairo MS, Chao NJ, Hayashi RJ, Nishihori T, Reshef R, Saad A, Shah A, Teshima T, Tallman MS, Wirk B, Spellman SR, Arora M, Martin PJ.:Tacrolimus versus Cyclosporine after Hematopoietic Cell Transplantation for Acquired Aplastic Anemia.:Biol Blood Marrow Transplant. 2015 Oct;21(10):1776-82.

英文症例報告

和文総説

  1. 豊嶋 崇徳:白血病・リンパ腫の治療 過去から未来へ:北海道医学雑誌 (0367-6102)90巻1号 Page9-11(2015.05):
  2. 豊嶋 崇徳:白血病・リンパ腫の治療 過去から未来へ:北海道医報 (0913-0217)1156号 Page31-35(2015.01)
  3. 豊嶋 崇徳:JAK阻害剤によるGVHDの制御:血液内科 (2185-582X)70巻5号 Page656-660(2015.05)
  4. 豊嶋 崇徳:臨床医歯学における微生物学の新展開 造血幹細胞移植における腸幹細胞、ニッチシステムと腸内細菌:無菌生物 (0910-0903)45巻1号 Page43-47(2015.09)
  5. 近藤 健:【慢性白血病の徴候を見逃さない】 好中球の増加:日本医事新報 (0385-9215)4773号 Page20-26(2015.10)
  6. 遠藤 知之:【危惧する感染症-院内感染防止対策-】 HIV感染症:Surgery Frontier (1340-5594)22巻3号 Page209-215(2015.09)
  7. 遠藤 知之:【すべての内科医のためのHIV感染症-長期管理の時代に】 HIV感染症にまつわるFAQ HIVに求められる感染対策(解説/特集):内科 (0022-1961)116巻5号 Page815-819(2015.11)
  8. 藤本 勝也, 豊嶋 崇徳:【新薬展望2015】 (第III部)治療における最近の新薬の位置付け(薬効別) 新薬の広場 血液腫瘍治療薬(解説/特集):医薬ジャーナル (0287-4741)51巻増刊 Page398-407(2015.01)
  9. 藤本 勝也, 畑中 佳奈子, 豊嶋 崇徳, 松野 吉宏:【リンパ腫学-最新の研究動向-】 リンパ組織の生物学とリンパ腫の発症機序 自己免疫疾患とリンパ腫発症(解説/特集);日本臨床 (0047-1852)73巻増刊8 リンパ腫学 Page123-127(2015.10)
  10. 藤本 勝也:ヒトレトロウイルス感染症の臨床 成人T細胞白血病を中心として(総説):Source: 産業動物臨床医学雑誌 (1884-684X)6巻3号 Page124-127(2015.11)
  11. 橋本 大吾, 豊嶋 崇徳:Front lines of basic and clinical research of SCT 腸管GVHDのkey players(解説):臨床血液 (0485-1439)56巻7号 Page807-814(2015.07)
  12. 橋本 大吾, 瓜生 英尚, 豊嶋 崇徳:真菌感染によるGVHD発症のメカニズム(解説);血液内科 (2185-582X)71巻6号 Page775-780(2015.12)
  13. 小野澤 真弘, 豊嶋 崇徳:【抗がん剤の副作用と支持療法-より適切な抗がん剤の安全使用をめざして-】 臓器別がん腫レジメンの副作用と対策 急性骨髄性白血病 Ara-C療法(解説/特集):日本臨床 (0047-1852)73巻増刊2 抗がん剤の副作用と支持療法 Page623-627(2015.02)
  14. 重松 明男, 豊嶋 崇徳:血液内科学 非血縁者間同種末梢血幹細胞移植の今後の展開(解説):医学のあゆみ (0039-2359)253巻2号 Page187-188(2015.04)
  15. 杉田 純一, 小杉 瑞葉, 豊嶋 崇徳:移植後シクロホスファミドを用いたHLA半合致移植の現状と課題(総説):日本造血細胞移植学会雑誌 (2186-5612)4巻1号 Page9-22(2015.01)
  16. 杉田 純一:【ICUで遭遇する血液疾患】(Part 2.)血液内科のクリティカルシンドローム 造血幹細胞移植に伴う重症合併症(感染症を除く) 造血幹細胞移植に伴う移植後合併症 時期により注意すべき合併症は異なる(解説/特集):Intensivist (1883-4833)7巻2号 Page375-382(2015.04)
  17. 松川 敏大, 北村 俊雄, 北浦 次郎:【マスト細胞の分化と機能の制御】 LMIR3/CD300fによる実験的腸炎の制御 LMIR3とセラミドの結合はATPによる腸管マスト細胞の活性化を抑制する(解説/特集):臨床免疫・アレルギー科 (1881-1930)64巻4号 Page374-379(2015.10)
  18. 早瀬 英子, 豊嶋 崇徳:【常在細菌と炎症・免疫疾患】 腸内細菌叢がGVHDにもたらす影響(解説/特集):Keynote R・A (2187-9680)3巻1号 Page24-28(2015.01)
  19. 藤本 勝也, 杉田 純一, 豊嶋 崇徳:【臨床血液学-最新情報と今後の展望2016(造血幹細胞移植)-】 HLA半合致移植の現状と展望(解説/特集):臨床血液 (0485-1439)57巻3号 Page288-297(2016.03)

和文原著

  1. 豊嶋崇徳 造血幹細胞移植 日本臨床腫瘍学会編:新臨床腫瘍学 (改訂第4版)-がん薬物療法専門医のために- 南江堂 212-215 2015
  2. 近藤 健、豊嶋 崇徳 第1寛解期における造血幹細胞移植の適応 EBM 血液疾患の治療 2015-2016 中外医学社 79-84 2015
  3. 藤本勝也 11. 代謝疾患 「ヘモクロマトーシス」 今日の治療指針 2016年版 医学書院 773-774 2016

和文著書

  1. 豊嶋崇徳 造血幹細胞移植 日本臨床腫瘍学会編:新臨床腫瘍学 (改訂第4版)-がん薬物療法専門医のために- 南江堂 212-215 2015
  2. 近藤 健、豊嶋 崇徳 第1寛解期における造血幹細胞移植の適応 EBM 血液疾患の治療 2015-2016 中外医学社 79-84 2015
  3. 藤本勝也 11. 代謝疾患 「ヘモクロマトーシス」 今日の治療指針 2016年版 医学書院 773-774 2016